Description
The HI30 antibody reacts with human CD45, one of the most abundant hematopoietic markers and one that is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, CD45RO and others.
The HI30 antibody is widely used as a marker for human CD45 expression on T cells, B cells, monocytes, macrophages, and NK cells.
Alternative Names |
Leukocyte Common Antigen, LCA, Ly-5 |
---|---|
Gene ID |
5788 |
Clone |
HI30 |
Isotype |
Mouse IgG1, kappa |
Reactivity |
Human |
Cross Reactivity |
Chimpanzee |
Format |
violetFluor™ 450 |
Application |
Flow Cytometry |
Catalog #: 75-0459-T025 -- 25 tests
Catalog #: 75-0459-T100 -- 100 tests
Please email us at cs@medikonia.com for any enquiry. To place an order, please include the catalog number(s) of the product(s) in the email.