Description
The HIB19 antibody reacts with human CD19, a 95 kDa glycoprotein which acts as a co-receptor, along with CD21, CD81 and CD225, in support of the functional B cell receptor (BCR). This complex provides antigen-specific recognition and subsequent activation of B cells to proliferate and differentiate into antibody-secreting cells (plasma cells) or memory B cells, which are crucial for secondary antigen encounter. CD19 is a lineage-differentiation marker, as its expression is detectable at the earliest B cell stages, through development, and is finally lost upon transition to mature plasma cells.
The HIB19 antibody is widely used as a phenotypic marker for CD19 expression on B cells, as well as on dendritic cell subsets.
|
Name |
violetFluor™ 450 Anti-Human CD19 (HIB19) |
|---|---|
|
Alternative Names |
Leu-12, B4 |
|
Gene ID |
930 |
|
Clone |
HIB19 |
|
Isotype |
Mouse IgG1, kappa |
|
Reactivity |
Human |
|
Format |
violetFluor™ 450 |
|
Application |
Flow Cytometry |
Catalog #: 75-0199-T025 -- 25 tests
Catalog #: 75-0199-T100 -- 100 tests
Please email us at cs@medikonia.com for any enquiry. To place an order, please include the catalog number(s) of the product(s) in the email.