Description

The OX-86 monoclonal antibody reacts with mouse CD134, a 50kD type 1 integral membrane glycoprotein and a member of the TNF-α receptor superfamily. CD134 is also known as OX40 and is expressed on activated CD4 and CD8 T cells. CD134 is the receptor for CD252 (OX40 ligand) and the interaction of this receptor-ligand pair is implicated in T-dependent humoral responses as well as numerous aspects of T cell expansion, survival and memory. Additionally, CD134 seems to play a significant role in the pathogenesis of some autoimmune diseases.

Recent Citations:

Lee W, Kingstad-Bakke B, Kedl RM, Kawaoka Y, Suresh M. CCR2 Regulates Vaccine-Induced Mucosal T-Cell Memory to Influenza A Virus. bioRxiv. 2021 Mar 25:2021.03.24.436901. doi: 10.1101/2021.03.24.436901. PMID: 33791695; PMCID: PMC8010722.

» View on PubMed

Catalog #:  65-1341-U025 -- 25 µg

Catalog #:  65-1341-U100 -- 100 µg

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TDS

SDS