Description
The HMa2 antibody reacts with mouse CD49b, a 150 kDa glycoprotein member of the integrin αfamily. CD49b, also known as integrin αalpha2, associates non-covalently with CD29 (integrin αbeta1) to form the VLA-2 heterodimer. VLA-2 integrin αs function as cellular receptors for collagen and laminin. CD49b is expressed by platelets, intestinal epithelial cells, NK cells, epithelial cells, and a subset of CD4+ T cells. CD49b plays an essential role in mediating the adhesion of cells to the extracellular matrix.
Name |
FITC Anti-Mouse CD49b (HMa2) |
---|---|
Cat. No. |
35-0491 |
Alternative names |
α2 integrin α, VLA-2 α chain, integrin α?2 chain, ITGA2, HMa2, BR; CD49 antigen-like family member B; CD49B; Collagen receptor; GPIa; integrin αalpha-2; ITGA2; Platelet membrane glycoprotein Ia; VLA-2; VLA-2 receptor, alpha 2 subunit; VLA-2 subunit alpha; VLA |
Gene ID |
16398 |
Clone |
HMa2 |
Isotype |
Armenian Hamster IgG |
Reactivity |
Mouse |
Format |
FITC |
Application |
Flow Cytometry |
Catalog #: 35-0491-U025 -- 25 µg
Catalog #: 35-0491-U100 -- 100 µg
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