Description

The FGK45 antibody reacts with mouse CD40, a 40-50 kDa glycoprotein member of the tumor necrosis factor receptor (TNFR) family. CD40 is constitutively expressed by antigen presenting cells, including dendritic cells, B cells, and macrophages. The interaction of CD40 and its ligand CD154, expressed on activated T cells, plays an essential role in mediating a broad range of immune and inflammatory responses including T cell dependent immunoglobulin class switching, germinal center formation, and the development of memory B cells.

The FGK45 clone is reported to be functionally useful for both in vitro and in vivo activation of CD40 expressing antigen presenting cells.

Catalog #: 20-8050-U025 -- 25 µg

Catalog #: 20-8050-U100 -- 100 µg

Please email us at cs@medikonia.com for any enquiry. To place an order, please include the catalog number(s) of the product(s) in the email.

TDS

SDS