Cytek PE Anti-Human CD154 (CD40L) (5C8)
PE Anti-Human CD154 (CD40L) (5C8). Catalog #: 50-1547
Description
The 5C8 antibody reacts with human CD154 which is also known as CD40L (CD40 ligand). CD154 is a 39kDa member of the TNF-α superfamily and is predominantly expressed on activated T cells but is also expressed on NK cells, mast cells, basophils, and eosinophils. CD154 binds to CD40, a molecule that is expressed on antigen presenting cells including B cells, monocytes/macrophages, and dendritic cells. The interaction of CD154 and CD40 regulates the activation of antigen presenting cells and is critical for B cell costimulation. The 5C8 antibody has been reported to block CD40L-CD40 interactions.
Name |
PE Anti-Human CD154 (CD40L) (5C8) |
---|---|
Cat. No. |
50-1547 |
Alternative Names |
CD40L, gp39, T-BAM, TRAP, Ly-62 |
Gene ID |
959 |
Clone |
5C8 |
Isotype |
Mouse IgG2a, κ |
Reactivity |
Human |
Cross Reactivity |
rhesus monkey, cynomolgus monkey |
Format |
PE |
Application |
Flow Cytometry |
Catalog #: 50-1547-T025 -- 25 tests
Catalog #: 50-1547-T100 -- 100 tests
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