Overview

Promote, rather than inhibit, neuronal activity and maturity in your cultured primary or human pluripotent stem cell (hPSC)-derived neurons. Based on the formulation by Bardy and Gage (Bardy et al. PNAS, 2015), BrainPhys™ Neuronal Medium is a serum-free basal medium that is optimized to yield a higher proportion of synaptically active neurons by mimicking the central nervous system (CNS) extracellular environment.

Use BrainPhys™ Neuronal Medium for long-term culture of hPSC- and CNS-derived neurons. To avoid shocking your cells with media changes, you can also use BrainPhys™ medium when performing functional assays, such as microelectrode array-based recordings or live-fluorescent imaging.

To ensure cell health in long-term serum-free culture, BrainPhys™ Neuronal Medium must be combined with an appropriate serum-replacement supplement, such as NeuroCult™ SM1 Neuronal Supplement and/or N2 Supplement-A. For your convenience, various BrainPhys™ kits that include the required supplement(s) for primary or hPSC-derived neurons are also available.

Subtype
Basal Media, Specialized Media
 

Cell Type
Neural Cells, PSC-Derived, Neurons, Pluripotent Stem Cells
 

Species
Human, Mouse, Rat
 

Application
Cell Culture, Differentiation, Maintenance
 

Brand
BrainPhys
 

Area of Interest
Disease Modeling, Drug Discovery and Toxicity Testing, Neuroscience, Stem Cell Biology
 

Formulation Category
Serum-Free

Product Advantages

- More representative of the brain’s extracellular environment

- Improved neuronal function and a higher proportion of synaptically active neurons

- Perform functional assays without changing media and shocking cells

- Supports long-term culture of ES/iPS cell- and CNS-derived neurons

- Rigorous raw material screening and quality control ensure minimal lot-to-lot variability

Catalog #: 05790

Please email us at cs@medikonia.com for any enquiry. To place an order, please include the catalog number(s) of the product(s) in the email.