Overview

Reliably generate mature human liver organoids that demonstrate hepatic functionality with HepatiCult™ Organoid Differentiation Medium (ODM) (Human), which includes all components required to support robust differentiation of hepatic organoids derived from fresh or cryopreserved human liver tissue.

Available either individually or as part of HepatiCult™ Organoid Kit (Human), HepatiCult™ ODM can be used to differentiate organoids initiated in HepatiCult™ Organoid Initiation Medium (Human) and/or expanded in HepatiCult™ Organoid Growth Medium (Human). Organoids differentiated with HepatiCult™ ODM express hepatocyte markers (ALB, CYP3A4, MRP4) and exhibit upregulated albumin secretion and CYP3A4 activity relative to undifferentiated organoids. These organoids can be adapted to a range of culture protocols, including suspension cultures and high-throughput assays.

 

Subtype
Specialized Media
 

Cell Type
Hepatic Cells
 

Species
Human
 

Application
Organoid Culture
 

Brand
HepatiCult
 

Area of Interest
Disease Modeling, Drug Discovery and Toxicity Testing, Epithelial Cell Biology, Organoids, Stem Cell Biology
 

Formulation Category
Serum-Free

What's Included

- HepatiCult™ Organoid Basal Medium (Human), 95 mL

- HepatiCult™ Differentiation Supplement (Human), 5 mL

Catalog #: 100-0383

Please email us at cs@medikonia.com for any enquiry. To place an order, please include the catalog number(s) of the product(s) in the email.