Overview

ImmunoCult™ Mouse Treg Differentiation Supplement contains a combination of recombinant mouse and human cytokines and a small molecule optimized to promote the differentiation of mouse naïve CD4+ T cells into regulatory T cells (Tregs). This supplement is intended for use with RPMI 1640 Medium (Catalog #36750) containing fetal bovine serum and other additives, as well as anti-mouse CD3 and anti-mouse CD28 monoclonal antibodies as activating agents.

This product is recommended for:
- Research into the regulation of mouse naïve T cell differentiation and Treg function
- Development of procedures to expand and polarize naïve T cells toward a Treg subset

Contains
- Recombinant mouse interleukin 2 (IL-2)
- Recombinant human transforming growth factor beta (TGF-β)
- All-trans retinoic acid (ATRA)
 

Subtype
Supplements
 

Cell Type
T Cells, T Cells, CD4+, T Cells, Regulatory
 

Species
Mouse
 

Application
Cell Culture, Differentiation, Expansion
 

Brand
ImmunoCult
 

Area of Interest
Immunology

Product Advantages

- Optimized for the induction of Tregs from naïve CD4+ T cells isolated from the spleen of a C57BL/6 mouse

- Supplied as a 100X concentrate; after thawing and mixing, the tube contents can be added directly to medium

Catalog #: 10957

Please email us at cs@medikonia.com for any enquiry. To place an order, please include the catalog number(s) of the product(s) in the email.