Overview

STEMdiff™ Astrocyte Differentiation Kit is used to rapidly and efficiently generate astrocytic precursors from neural progenitor cells (NPCs) derived from human pluripotent stem cells (hPSCs) using STEMdiff™ SMADi Neural Induction Kit (Catalog #08581). These astrocytic precursors are then matured further into astrocytes using STEMdiff™ Astrocyte Maturation Kit (Catalog #100-0016). Using this system, a highly pure population of astrocytes (an average of > 70% S100B-positive and > 60% GFAP-positive astrocytes; < 15% doublecortin-positive neurons) can be generated from hPSCs in as few as 7 weeks and can be maintained long term in culture. Cells derived using these products are versatile tools for modeling human neurological development and disease, drug screening, toxicity testing, and cell therapy validation.

Subtype
Specialized Media
 

Cell Type
Neural Cells, PSC-Derived, Neural Stem and Progenitor Cells
 

Species
Human
 

Application
Cell Culture, Differentiation
 

Brand
STEMdiff
 

Area of Interest
Disease Modeling, Drug Discovery and Toxicity Testing, Neuroscience
 

Formulation Category
Serum-Free

Product Advantages

- Defined and serum-free

- Supports highly efficient generation of functional astrocytes

- Optimized for differentiation from neuronal progenitor cells generated using STEMdiff™ SMADi Neural Induction Kit

- Enables reproducible generation of cortical-type astrocytic precursors derived from multiple human ES and iPS cell lines

What's Included

- STEMdiff™ Astrocyte Differentiation Basal Medium, 80 mL

- STEMdiff™ Astrocyte Differentiation Supplement, 20 mL

Catalog #: 100-0013

Please email us at cs@medikonia.com for any enquiry. To place an order, please include the catalog number(s) of the product(s) in the email.