Overview

Generate physiologically relevant blood vessel organoids—easily and with high yield—for your tissue repair and regeneration studies or to model vascular disease in vitro by using STEMdiff™ Blood Vessel Organoid Kit.

Use STEMdiff™ Blood Vessel Organoid Kit for efficient and reproducible generation of blood vessel organoids from human pluripotent stem cells (hPSCs), with the option to scale up for high-throughput screening in a 96-well format. Compared to homemade organoid culture media formulations, organoids generated with this easy-to-use kit develop extensive and physiologically relevant vascular networks and strong endothelial cell-pericyte interactions. Blood vessel organoids generated using this kit have CD31+/CD34+/CD144+/KDR+ endothelial cells and PDGFR-β+/CD146+/SMA+/NG-2+ pericytes.The simple protocol also eliminates the need for serum screening and labor-intensive protocol optimization, so you can spend more time on what matters—your experiments.

Use STEMdiff™ Blood Vessel Organoid Kit with mTeSR™ Plus or mTeSR™1 culture media for an easy transition from hPSCs to organoids. For your convenience, STEMdiff™ Blood Vessel Organoid Maturation Medium, required for the maturation of hPSC-derived blood vessel organoids, is available either as a part of the kit or for individual sale. To differentiate hPSCs to endothelial cells, use our STEMdiff™ Endothelial Differentiation Kit.

Subtype
Specialized Media, Supplements
 

Cell Type
Endothelial Cells, Endothelial Cells, PSC-Derived
 

Species
Human
 

Application
Functional Assay, Organoid Culture, Toxicity Assay
 

Brand
STEMdiff
 

Area of Interest
Angiogenic Cell Research, Disease Modeling, Drug Discovery and Toxicity Testing, Endothelial Cell Biology

Product Advantages

- Generates physiologically relevant 3D blood vessel organoids ideal for disease modeling and drug discovery

- Provides a standardized protocol with optimized reagents for efficient generation of hPSC-derived organoids

- Supports high-throughput scalability in a 96-well format for drug discovery or drug testing

What's Included

- STEMdiff™ Blood Vessel Organoid Aggregation Basal Medium, 60 mL

- STEMdiff™ Blood Vessel Organoid Aggregation Supplement, 15 mL

- STEMdiff™ Blood Vessel Organoid Induction Basal Medium, 100 mL

- STEMdiff™ Blood Vessel Organoid Induction Supplement, 1 mL

- STEMdiff™ Blood Vessel Organoid Mesodermal Induction Supplement, 1 mL

- STEMdiff™ Blood Vessel Organoid Vascular Induction Supplement, 1 mL

- STEMdiff™ Blood Vessel Organoid Maturation Medium, 100 mL (Catalog #100-0658)

Catalog #: 100-0651

Please email us at cs@medikonia.com for any enquiry. To place an order, please include the catalog number(s) of the product(s) in the email.