Overview

Maintain human intestinal organoids long term as a model system for studying intestinal research, disease modeling, drug discovery, and compound screening. Use serum-free STEMdiff™ Intestinal Organoid Growth Medium (OGM) for extended, consistent culture of human pluripotent stem cell (hPSC)-derived intestinal organoids.

Based on the formulation published by Spence et al. (Nature 2011), STEMdiff™ Intestinal OGM is optimized for efficient and reproducible organoid generation and expansion across hPSC lines. Use STEMdiff™ Intestinal OGM to mature mid-/hindgut spheroids differentiated from hPSCs using STEMdiff™ Intestinal Organoid Kit. The spheroids will mature into intestinal organoids that you can cryopreserve or maintain long-term through passaging. Intestinal organoids cultured in STEMdiff™ Intestinal OGM exhibit a cellular composition and organization that models the developing intestinal epithelium and associated mesenchyme, making them a convenient model system with direct relevance to the developing intestine.

Cell Type
Endoderm, PSC-Derived, Intestinal Cells
 

Species
Human
 

Application
Cell Culture, Differentiation, Organoid Culture
 

Brand
STEMdiff
 

Area of Interest
Disease Modeling, Drug Discovery and Toxicity Testing, Epithelial Cell Biology
 

Formulation Category
Serum-Free

What's Included

- STEMdiff™ Intestinal Organoid Basal Medium, 100 mL

- STEMdiff™ Intestinal Organoid Supplement, 2 mL

Catalog #: 05145

Please email us at cs@medikonia.com for any enquiry. To place an order, please include the catalog number(s) of the product(s) in the email.