Overview

The STEMdiff™ Midbrain Neuron Maturation Kit (Catalog #100-0041) is used in conjunction with the STEMdiff™ Midbrain Neuron Differentiation Kit (Catalog #100-0038) to generate a mixed population of midbrain-type neurons from neural progenitor cells derived from human pluripotent stem cells. These media will produce a population of midbrain neurons (≥ 15% TH-positive dopaminergic neurons; ≥ 90% class III βtubulin-positive neurons; < 10% GFAP-positive astrocytes). Cells derived using these products are versatile tools for modeling human neurological development and disease, drug screening, toxicity testing, and cell therapy validation.

Subtype
Specialized Media
 

Cell Type
Dopaminergic Neurons, Neural Cells, PSC-Derived, Neurons
 

Species
Human
 

Application
Cell Culture, Characterization, Differentiation, Functional Assay, Immunocytochemistry, Phenotyping
 

Brand
STEMdiff
 

Area of Interest
Disease Modeling, Drug Discovery and Toxicity Testing, Neuroscience
 

Formulation Category
Serum-Free

Product Advantages

- Defined and serum-free

- Supports highly efficient generation of midbrain-like functional neurons from hPSC-derived neuronal precursors

- Produces a population of TH-positive neurons (>15%) that can be maintained long term in culture

- Optimized for maturation of midbrain neuronal precursors generated using the STEMdiff™ Midbrain Neuron Differentiation Kit

- Supports neuronal activity for physiologically relevant results

- Enables reproducible maturation of midbrain-type neuronal precursors derived from multiple human ES and iPS cell lines

What's Included

- STEMdiff™ Midbrain Neuron Maturation Supplement, 25 mL

- BrainPhys™ Neuronal Medium, 100 mL

Catalog #: 100-0041

Please email us at cs@medikonia.com for any enquiry. To place an order, please include the catalog number(s) of the product(s) in the email.