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STEMdiff™ Motor Neuron Maturation Kit

Differentiation and maturation kits for generation of motor neurons from human pluripotent stem cells

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Overview

Reduce the risk of culture failure by maturing and maintaining motor neuron cells using the STEMdiff™ Motor Neuron Maturation Kit. This kit combines neurophysiological BrainPhys™ Medium (Catalog #05790)—proven to support long-term activity and maturation—with the supplements needed to produce functional motor neuron cultures.

Cells matured with the STEMdiff™ Motor Neuron Maturation Kit exhibit high-level expression of expected motor neuron markers, including ChAT (>40%), across multiple cell lines. Use the resulting motor neuron cultures in a variety of applications, such as modeling human neurological disease or toxicity testing. The STEMdiff™ Motor Neuron Maturation Kit can also support your co-culture with muscle cells generated using the MyoCult™ Differentiation Kit (Catalog #05965) or with microglia generated using the STEMdiff™ Microglia Differentiation Kit (Catalog #100-0019).

 

Subtype
Specialized Media
 

Cell Type
Neural Cells, PSC-Derived, Neural Stem and Progenitor Cells, Neurons
 

Species
Human
 

Application
Cell Culture, Differentiation, Genome Editing
 

Brand
STEMdiff
 

Area of Interest
Disease Modeling, Drug Discovery and Toxicity Testing, Neuroscience
 

Formulation Category
Serum-Free

 

Product Advantages

- Differentiate motor neurons from human induced pluripotent stem cell lines (iPSCs) in only 14 days
- Streamline motor neuron culture with a simple, scalable workflow
- Produce physiologically relevant results with integrated BrainPhys™ media that supports neuronal activity and maturation
- Model the complexities of cell-cell interactions by pairing with compatible differentiation kits for co-culture applications

 

What's Included

- BrainPhys™ Neuronal Medium, 100 mL

- STEMdiff™ Motor Neuron Maturation Supplement, 25 mL

Catalog #: 100-0872

Please email us at cs@medikonia.com for any enquiry. To place an order, please include the catalog number(s) of the product(s) in the email.