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StemSpan™ B Cell Differentiation Supplement 1 (20X)

Supplement 1 for the expansion and differentiation of human CD34+ HSPCs to B lymphoid progenitors

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Overview

Support the expansion and differentiation of CD34+ hematopoietic stem and progenitor cells (HSPCs) isolated from cord blood with StemSpan™ B Cell Differentiation Supplement 1 (20X). This supplement contains a combination of recombinant cytokines and other additives formulated to selectively and efficiently promote the expansion and differentiation of HSPCs to B lymphoid progenitors containing ProB and PreB cells.

For your convenience, this supplement is available either individually or as part of the StemSpan™ B Cell Generation Kit and is intended for use with StemSpan™ Serum-Free Expansion Medium II (SFEM II). Continuing the protocol, StemSpan™ B Cell Differentiation Supplement 2 (20X) provides stimuli to enable further differentiation of B lymphoid progenitor cells to B cell progenitors. Additionally, using StemSpan™ B Cell Differentiation Supplement 3 (20X) in tandem with StemSpan™ B Cell Differentiation Supplement 4 (20X) selectively differentiates the B cell progenitors to B cells and antibody-secreting cells.

 

Subtype
Supplements
 

Cell Type
B Cells, Hematopoietic Stem and Progenitor Cells
 

Species
Human
 

Application
Cell Culture, Differentiation, Expansion
 

Brand
StemSpan
 

Area of Interest
Immunology
 

Formulation Category
Serum-Free

 

Product Advantages

- Obtain high yields of B lymphoid progenitors containing proB and preB cells

- Use as part of the StemSpan™ B Cell Generation Kit protocol

Catalog #: 100-1251

Please email us at cs@medikonia.com for any enquiry. To place an order, please include the catalog number(s) of the product(s) in the email.