Overview

StemSpan™ Megakaryocyte Expansion Supplement (100X) contains a combination of recombinant human cytokines formulated to selectively promote the expansion and differentiation of human megakaryocyte progenitor cells from CD34+ cells isolated from human cord blood (CB) or bone marrow (BM) samples.

StemSpan™ Megakaryocyte Expansion Supplement (100X) is intended for use in combination with any of the following StemSpan™ media:
- StemSpan™ SFEM (Catalog #09600)
- StemSpan™ SFEM II (Catalog #09605)
- StemSpan™-XF (Catalog #100-0073)
- StemSpan™-AOF (Catalog #100-0130)

When added to serum-free medium, StemSpan™ Megakaryocyte Expansion Supplement typically promotes the production of hundreds of megakaryocytes per input CD34+ cell in 14-day liquid cultures initiated with CD34+ human CB cells. See data tab for more details.

Contains
- Recombinant human stem cell factor (SCF)
- Recombinant human interleukin 6 (IL-6)
- Recombinant human interleukin 9 (IL-9)
- Recombinant human thrombopoietin (TPO)
 

Subtype
Supplements
 

Cell Type
Hematopoietic Stem and Progenitor Cells, Megakaryocytes
 

Species
Human
 

Application
Cell Culture, Differentiation, Expansion
 

Brand
StemSpan
 

Area of Interest
Stem Cell Biology, Transplantation Research
 

Formulation Category
Serum-Free

Product Advantages

- Formulated to produce large numbers of human megakaryocytes in liquid cultures initiated with CD34+ CB or BM cells.

- Optimized for use with StemSpan™ media. When combined with StemSpan™ SFEM II in particular, supports up to 2-fold higher expansion of megakaryocytes from human CD34+ CB cells than other serum-free media on the market.

- Supplied as a 100X concentrate. After thawing and mixing, the tube contents can be added directly to any hematopoietic cell expansion medium of choice.

Catalog #: 02696

Please email us at cs@medikonia.com for any enquiry. To place an order, please include the catalog number(s) of the product(s) in the email.