Overview

Reduce the validation burden for your laboratory and effectively and reliably enrich plasma cells with the EasySep™ Human Bone Marrow CD138 Positive Selection Kit. This kit is an in vitro diagnostic (IVD) medical device for hematopoietic cell enrichment available in Canada, Europe, the United Kingdom, and the United States, and is indicated for use with validated diagnostic assays as part of the pre-analytical workflow. The intended use of this kit is to enrich bone marrow samples, from patients who may or are known to have multiple myeloma, for CD138+ cells using immunomagnetic positive selection.

The National Comprehensive Cancer Network® (NCCN Guidelines Version 2.2020 Multiple Myeloma) recommends using enriched plasma cells from bone marrow aspirations when performing fluorescence in situ hybridization (FISH) analysis for multiple myeloma testing. Enriching bone marrow samples for CD138+ cells has been reported to increase the rate and frequency of chromosomal abnormalities detected by FISH (e.g. Shin SY et al. Int J Hematol, 2012; Shetty S et al. Int J Hematol, 2012), which may help define effective treatment strategies against multiple myeloma.

Designed for use with the “The Big Easy” EasySep™ Magnet and EasySep™ Buffer (IVD) to isolate cells without the use of columns, the EasySep™ Human Bone Marrow CD138 Positive Selection Kit includes the antibodies and magnetic particles required to label CD138+ cells for separation. The easy-to-follow protocol results in labeled CD138+ cells that remain in the tube after unlabeled cells are poured off. This kit is indicated for in vitro diagnostic use by laboratory professionals; the end user is responsible for determining whether the product is suitable for their specific application(s).

Note: Ref #100-0748 is the Regulatory Product ID and should not be used for ordering.

Magnet Compatibility
- “The Big Easy” EasySep™ Magnet (Catalog #18001)
 

Subtype
Cell Isolation Kits
 

Cell Type
Myeloma
 

Species
Human
 

Sample Source
Bone Marrow
 

Selection Method
Positive
 

Application
Cell Isolation
 

Brand
EasySep
 

Area of Interest
Cancer
 

Product Advantages

- Isolate plasma cells quickly and reliably

- Follow an easy-to-use and column-free protocol

- Reduce your validation burden by using an IVD product

- Enhance the sensitivity of downstream fluorescence in situ hybridization (FISH)

What's Included

- EasySep™ Human Bone Marrow CD138 Positive Selection Kit (Catalog #100-1133)

    - EasySep™ Human Bone Marrow CD138 Positive Selection Cocktail, 3 x 1 mL

    - EasySep™ Dextran RapidSpheres™ 50105, 3 x 1 mL

    - EasySep™ Red Blood Cell Lysis Buffer, 10X Concentrate, 1 x 20 mL

Catalog #: 100-1133

Please email us at cs@medikonia.com for any enquiry. To place an order, please include the catalog number(s) of the product(s) in the email.