Product Overview

Chronic bronchitis is marked by long-term cough and excess mucous. Emphysema leads to the destruction of the lungs over time. Most people with COPD have a combination of both conditions. Usually COPD is associated with bronchial epithelium changes.

Cryopreserved diseased human bronchial epithelial cells from donors diagnosed with COPD are screened for air liquid interface differentiation. These cells test negative for mycoplasma, bacteria, yeast, and fungi. HIV-1, hepatitis B and hepatitis C are not detected for all donors and/or cell lots. A Certificate of Analysis is provided for each cell lot purchased.

Our catalog number 00195275S are suitable for air-liquid interface studies and are guaranteed to promote full differentiation of the airway epithelium expressed by the formation of a polarized epithelium with good barrier function (transepithelial resistance), secretory phenotype (mucin secretion) and ciliogenesis. Differentiation usually will occur by day 22 in culture.

Benefits

• All cells test negative for mycoplasma, bacteria, yeast, and fungi

• HIV-1, Hepatitis B and Hepatitis C are not detected for all donors and/or cell lots

• Certificate of Analysis provided for every cell lot

Content

1 x Cryopreserved ampule containing ≥ 500,000 cells

Recommended Medium

Lonza B-ALI™ Bronchial Air-Liquid Interface Medium BulletKit™

Catalog #: 195275S

Please email us at cs@medikonia.com for any enquiry. To place an order, please include the catalog number(s) of the product(s) in the email.

Instructions for Proper Use and Culture of Airway Epithelial Cells

Instructions for Proper Use and Culture

Reference guidefor human and animal cells from normal to diseased, fresh and cryopreserved