For Whole Blood Collection and Preservation of Cell-Free Circulating DNA and RNA

Norgen's cf-DNA/cf-RNA Preservative Tubes are closed, evacuated plastic tubes for the collection and the preservation of cf-DNA, circulating tumor DNA, cf-RNA and circulating tumor cells in human whole blood samples during storage and shipping.

• - CE-IVD marked in accordance with EU Directive 98/79/EC
• - Ideal for use in in vitro diagnostic workflows
• - Fixative-free preservative, no cross-linking of DNA
• - Preserve cf-DNA/ct-DNA for 30 days at ambient temperature and for up to 8 days at 37°C.
• - Preserve cf-RNA for 30 days at ambient temperature
• - Preserve Circulating Tumour Cells (CTCs) for 14 days at ambient temperature
• - No plasma volume loss after shipping/transportation
• - Prevent hemolysis allowing better separation of plasma
• - Prevent apoptosis of blood cells and fragmentation of genomic DNA
• - Produce high quality/quantity of plasma cf-DNA/ct-DNA/cf-RNA
• - Vacuumed to draw 8.4 mL of blood in 10 mL tubes
• - The procedure for plasma isolation using this kit is compliant with ISO 20186-3:2019

Intended for in vitro diagnostics use.

cf-DNA/cf-RNA Preservative Tubes Dx

Norgen's cf-DNA/cf-RNA Preservative Tubes Dx are closed, evacuated plastic tubes for the collection and the preservation of cf-DNA, circulating tumor DNA, cf-RNA and circulating tumor cells in human whole blood samples during storage and shipping. Using these tubes in combination with Norgen's Plasma/Serum Cell-Free Circulating DNA Purification Kits or Norgen's Plasma/Serum RNA Purification Kits enables the purification and concentration of an inhibitor-free cf-DNA/ct-DNA/cf-RNA in a very small elution volume. 

These tubes are ideal for collecting and preserving cf-DNA and cf-RNA samples for in vitro diagnostic use for medical purposes.

Performance

Norgen's cf-DNA/cf-RNA Preservative Tubes Dx abridge the collection/processing of whole blood for the subsequent purification of cf-DNA and/or cf-RNA. The cf-DNA/cf-RNA Preservative Tubes Dx preserve and inhibit the programmed cell-death (apoptosis) of the blood, hence preventing the release of intracellular DNA/RNA into plasma. Whole blood samples can be shipped and stored at room temperature for the subsequent processing of plasma. The cf/ct DNA and cf-RNA levels are stable for up to 30 days at room temperature. The cf-DNA is also stable for up to 8 days at 37°C.

Kit Specifications

Tube Size:

• 16 x 100mm

Tube Type:

• PET Tube

Blood Draw Volume:

• 8.4 mL in 10 mL Tubes

Preservative Volume:

• 1.6 mL

Recovered Plasma Volume:

• Approximately 6-7 mL (not affected by shipping)

Anticoagulant:

• Proprietary

Preservative:

• Non formaldehyde - Proprietary preservation agent

Length of cf-DNA Preservation:

• Up to 30 days at room temperature (15-25°C)

• Up to 8 days at 37°C

Length of cf-RNA Preservation:

• Up to 30 days at room temperature (15-25°C)

Length of CTCs Preservation: 

• Up to 14 days at room temperature (15-25°C)

Catalog #: Dx63950

Please email us at cs@medikonia.com for any enquiry. To place an order, please include the catalog number(s) of the product(s) in the email.

Protocols

cf-DNA/cf-RNA Preservative Tubes Dx - Protocol (50 Tubes)

Supplementary Protocols

cf-DNA/cf-RNA Preservative Tubes Dx - Mixing Instructions

cf-DNA/cf-RNA Preservative Tubes - Supplementary Protocol for RNA/DNA/Protein Purification from Leukocytes recovered from cf-DNA

Product Information Sheets

Product Flyer

Application Notes

Assessing the Effect of Simulated Shipping on Cell-Free DNA in Blood Collected in Norgen, Streck and EDTA Tubes

Product Flyers

cf-DNA/cf-RNA Preservative Tubes