All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Biological Description

Description: Cetuximab (anti-EGFR) a novel molecular-targeted agentis an inhibitor of EGFR monoclonal humanized antibody interacting with the extracellular binding site of EGFR to block ligand stimulation.

Targets&IC50: EGFR:0.147 nM (Kd, Fixed A431 cells) , Soluble EGFR:0.201 nM (Kd)

Chemical Properties

Molecular Weight: 152kd

Formula: C107H179N35O36S7

CAS No.: 205923-56-4

Storage & Solubility

Storage

store at -20 ℃

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Catalog #: T9905

Please email us at cs@medikonia.com for any enquiry. To place an order, please include the catalog number(s) of the product(s) in the email.

References and Literature

1. Huang S M , Bock J M , Harari P M . Epidermal Growth Factor Receptor Blockade with C225 Modulates Proliferation, Apoptosis, and Radiosensitivity in Squamous Cell Carcinomas of the Head and Neck1[J]. Cancer Res, 1999, 59(8):1935-1940.

2. H, Gustafsso, A, et al. EPR Oximetry of Cetuximab-Treated Head-and-Neck Tumours in a Mouse Model[J]. Cell Biochemistry & Biophysics, 2017.