TheraPEAKTM X-VIVOTM Media Series are a high performing media that provides nutritionally adequate and balanced environments for a variety of hematopoietic cells including:
- T cells
- Natural killer cells (NK)
- Peripheral blood lymphocytes (PBL)
- Tumor infiltrating lymphocytes (TIL)
- Dendritic cells (DC)
- Human monocytes
- Macrophage cells
TheraPEAKTM X-VIVOTM 10 Media formulations are designed to support slower growing, less mature cells such as hematopoetic stem cells and natural killer cells. TheraPEAKTM X-VIVOTM 10 also supports the generation of Lymphokine activated killer (LAK) cells and peripheral blood lymphocytes (PBL).
TheraPEAKTMX-VIVOTM 10 Media is available as a 1X liquid in 3 convenient formulations as off the shelf catalog items. Additional customization of packaging available.
X-VIVOTM 10, catalog number (BE)04-380Q contains L-glutamine, gentamicin, and phenol red and is only available labeled for research use only.
TheraPEAKTM X-VIVOTM 10, catalog number (BE)BP04-743Q contains L-glutamine but does not contain gentamicin or phenol red.
TheraPEAKTM X-VIVOTM 10, catalog number (BE)BP02-055Q contains L-glutamine and recombinant transferrin but does not contain gentamicin or phenol red. The recombinant transferrin replaces native human transferrin.
TheraPEAKTM X-VIVOTM 15 Media are mostly known for its ability to support the proliferation of purified CD3+ cells isolated from peripheral blood and human tumors making it well suited for CAR-T applications.
TheraPEAKTM X-VIVOTM 15 Media are similar in composition to X-VIVOTM 10 Media but is better suited for rapidly growing cells, specifically cells of the immune system.
All TheraPEAKTM Products are produced according to applicable GMP standards and follow the USP/EP guidance for cell and gene therapy raw materials. It is the end user's responsibility to ensure full compliance with local regulations in terms of safety assessments and effective removal prior to patient exposure.
TheraPEAKTM Media Products are produced according to applicable GMP raw material standards and are intended to support GMP manufacturing. TheraPEAKTM Media Products are produced at FDA registered manufacturing sites with an ISO 13485 certified quality management system.