Product Overview

COPD Airway Cells include lung fibroblasts, bronchial epithelial and bronchial smooth muscle cells. Bronchial epithelial cells from COPD donors are isolated from epithelial lining of airways above bifurcation of the lungs.                                  

Cryopreserved Diseased Human Bronchial Epithelial cells from COPD donors test negative for mycoplasma, bacteria, yeast, and fungi. HIV-1, hepatitis B and hepatitis C are not detected for all donors and/or cell lots.

A Certificate of Analysis is provided for each cell lot purchased. Our catalog number 00195275S are suitable for air-liquid interface studies and are guaranteed to promote full differentiation of the airway epithelium expressed by the formation of a polarized epithelium with good barrier function (transepithelial resistance), secretory phenotype (mucin secretion) and ciliogenesis. Differentiation usually will occur by day 22 in culture.

Benefits

• All cells test negative for mycoplasma, bacteria, yeast, and fungi

• HIV-1, Hepatitis B and Hepatitis C are not detected for all donors and/or cell lots

• Certificate of Analysis provided for every cell lot

Applications

• Gene expression pathways   

• Phenotypic changes to compounds   

• Transfect diseased cells   

• Co-culture with immune cells   

• Airway remodeling studies   

• Cellular interactions

Content

1 x Cryopreserved ampule containing ≥500,000 cells

Recommended Medium

Lonza BEGM™ Bronchial Epithelial Cell Growth Medium BulletKit™

Catalog #: 195275

Please email us at cs@medikonia.com for any enquiry. To place an order, please include the catalog number(s) of the product(s) in the email.

Instructions for Proper Use and Culture of Airway Epithelial Cells

Reference guidefor human and animal cells from normal to diseased, fresh and cryopreserved